RECOMMENDED DOSAGE OF CHROMIUM PICOLINATE FOR DIABETES TRIAL
In a placebo-controlled trial that enrolled 59 subjects diagnosed with high glucose levels, insulin resistance, or metabolic syndrome, taking either 500 micrograms or 1,000 micrograms of chromium (as chromium picolinate) daily for six months did not change any of the measured metabolic parameters. While high heart rate is not typically considered part of metabolic syndrome, it is linked to heart disease.
In one placebo-controlled trial with 70 subjects affected by metabolic syndrome, those receiving 300 micrograms of chromium (in the form of chromium-enriched yeast) per day had no changes in measures of glucose and lipid metabolism but had a decrease in resting heart rate.
However, clinical trials examining the effects of chromium supplementation in people with metabolic syndrome have been mixed.
A 23-year observational study found those with poorer baseline chromium status were more likely to develop metabolic syndrome than those with better chromium status. It has been widely studied for its potential benefits in people with insulin resistance and type 2 diabetes.
Many doctors recommend up to 1,000 mcg per day for people with diabetes.Ĭhromium is a mineral needed in trace amounts by the body. Studies showing beneficial effects from chromium supplementation have generally used 200 mcg per day or more. Because of its ability to help regulate dopamine and serotonin activity, some researchers propose chromium may be especially beneficial in people with type 2 diabetes who also suffer from depression or binge eating. A meta-analysis of 28 other randomized controlled trials concluded that chromium supplementation, particularly chromium chloride or chromium picolinate, reduces fasting blood glucose levels, triglyceride levels, and hemoglobin A1c values, and increases HDL-cholesterol levels. In addition, chromium supplementation led to lower levels of inflammatory markers and higher antioxidant capacity. In one placebo-controlled trial that included 64 participants with type 2 diabetes and heart disease, taking 200 mcg per day of chromium was associated with greater weight loss, lower fasting glucose and insulin levels, improved insulin sensitivity, and reduced blood pressure after four months. Furthermore, chromium supplementation has been shown to improve glucose control, insulin sensitivity, and other metabolic variables in people with insulin resistance and type 2 diabetes. For a supplement, little scientific support.Ĭhromium status appears to be an important factor in glucose metabolism: individuals with lower chromium levels are more likely to have type 2 diabetes or pre-diabetes than those with higher levels, and low chromium status is associated with poor glycemic control and insulin resistance in people with type 2 diabetes. We hope this provides you with a helpful resource to make informed decisions towards your health and well-being.ģ Stars Reliable and relatively consistent scientific data showing a substantial health benefit.Ģ Stars Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit.ġ Star For an herb, supported by traditional use but minimal or no scientific evidence. To help you make educated decisions, and to better understand controversial or confusing supplements, our medical experts have digested the science into these three easy-to-follow ratings. While there is no way to predict whether a vitamin, mineral, or herb will successfully treat or prevent associated health conditions, our unique ratings tell you how well these supplements are understood by the medical community, and whether studies have found them to be effective for other people.įor over a decade, our team has combed through thousands of research articles published in reputable journals. Our proprietary “Star-Rating” system was developed to help you easily understand the amount of scientific support behind each supplement in relation to a specific health condition.
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